Ameloblastoma is a rare, benign or cancerous tumor of odontogenic epithelium much more commonly appearing in the lower. Histopathology of ameloblastoma of the jaws; some critical observations based on a 40 years single institution experience. Doenja Hertog 1. Cases Series. Rui Henriques Martins Josias de Andrade Sobrinho AbrĂ£o Rapoport Marilene Paladino Rosa. Histopathologic features and management of .

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Dental tumors ICD-O These are most readily recognizable and common type of ameloblastoma histologically. They present histologically with follicular or plexiform pattern as well as acanthomatous pattern. Additionally, because abnormal cell growth easily infiltrates and destroys surrounding bony tissues, wide surgical excision is required to treat this disorder.

From Wikipedia, the free encyclopedia. Because of the invasive nature of the growth, excision of normal tissue near the tumor margin is often required. Of the 28 patients initially treated by enucleation, 17 patients experienced one or more recurrences, including 11 patients treated previously elsewhere.

Click here for patient related inquiries. Therefore, one would expect a younger age than in patients diagnosed with an ameloblastoma in some of the developing countries. Ameloblastoma grow slowly and usually are asymptomatic until a swelling is noticed.

The histopathologic reclassification showed that follicular ameloblastoma 11 cases affected the body of the mandible in 6 cases, the ascendant ramus in 3 cases and the angle in 2 cases. Recurrence is common, although the recurrence rates for block resection followed by bone graft are lower than those of enucleation and curettage.

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Wikimedia Commons has media related to Ameloblastoma. Ameloblastoma with mucous cells: Anastassov et al 11 have reported that radiotherapy alone or ameloblasto,a with chemotherapy is only indicated for patients of advanced age.

In the Netherlands most ameloblastomas are found during routine radiographic examination by the dentist. histopayhology

Head and Neck: Odontogenic tumor: Ameloblastoma

J Oral Maxillofac Surg ; New author database being installed, click here for details. This website is intended for pathologists and laboratory personnel, who understand that medical information is imperfect and must be interpreted using reasonable medical judgment.

J Oral Pathol Med. A clinico-pathological comparison between mandibular and maxillary ameloblastomas in Sri Lanka. In Figure 2the plexiform type is shown to have degeneration of the stroma with the formation of cysts with few areas similar to the starry reticulum, thus justifying its low aggressiveness. Report of a case”. There are six histopathologic subtypes which have been identified for ameloblastoma i. Luminal type and B: Comparing our results with the literature demonstrated to us that this tumor may be considered to be a worldwide problem due to the similarity in clinical findings among different ethnic groups.

A review of cases from the literature. For example, in two patients with an initial plexiform and mixed type ameloblastoma, the recurrence showed a desmoplastic variant. Using the Regeze, Kerr and Courtney classificationwe diagnosed follicular tumor in 11 cases, plexiform in 6 cases and unicystic in 3 cases, and performed surgical resection with a safety margin of 1.

In a detailed study of patients, chemotherapy and radiation therapy seemed to be contraindicated for the treatment of ameloblastomas.


D ICD – The various genetic events reported include: The plexiform ameloblastoma shows epithelium proliferating in a ‘cord like fashion’, hence the name ‘plexiform’. Arch Amelohlastoma Head Neck Surg. This variant histologically presents as a single cyst lined by ameloblastomatous epithelium and is divided into several subgroups based on pattern and extent of ameloblastomatous proliferation in relation to cyst wall.

Yet, amelioblastomas show more bone expansion and seldom show high density areas.


It shows equal sex predilection with no specific racial predominance. Plexiform ameloblastoma with anastomosing strands and cords of tumour cells H. It presents clinically similar to a dentigerous cyst and is usually associated with an impacted tooth usually 3rd molars. Therapy is not the main focus of this paper, but when resection is essential, bone reconstruction using plates and titanium screws or an integrated bone implant may become necessary.

They typically infiltrate through the medullary bone, therefore the radiographic margins are not accurate indicators of the extent of involvement.

This result does not give support to the belief that ameloblastomas in children behave in a less aggressive way than in adults Introduction The ameloblastoma is a histologically almost always benign odontogenic tumour of the jaw bones.

Differential diagnosis of conventional multicystic ameloblastoma Malignant ameloblastoma Also called metastasizing ameloblastoma Identical histology but with metastasis Ameloblastic carcinoma Variable features of amelobastoma: The aim of the present study is to examine all cases of intraosseous benign ameloblastomas treated between and in a single institution and to look for a possible correlation between the histopathological aspects and the demographical and clinical parameters, as well as the treatment outcome.


Additionally, squamous cells with abundant cytoplasm and central nucleus can also be seen if there is evidence of squamous metaplasia.